I9386
myo-Inositol 1,3,4,6-tetrakis-phosphate ammonium salt
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About This Item
Empirical Formula (Hill Notation):
C6H16O18P4 · xNH3
CAS Number:
Molecular Weight:
500.08 (free acid basis)
PubChem Substance ID:
UNSPSC Code:
12352201
InChI
1S/C6H16O18P4.H3N/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14;/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);1H3/t1-,2+,3-,4+,5-,6+;
InChI key
ANQVRWQIKKBLLK-PWRMZBPBSA-N
SMILES string
N.O[C@H]1[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O
storage temp.
−20°C
Biochem/physiol Actions
Accumulates with angiotensin II stimulation; stimulates intracellular Ca++ release.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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T Balla et al.
Biochemical and biophysical research communications, 148(1), 199-205 (1987-10-14)
Angiotensin II stimulates the formation of several inositol polyphosphates in cultured bovine adrenal glomerulosa cells prelabelled with [3H] inositol. Analysis by high performance anion exchange chromatography of the inositol-phosphate compounds revealed the existence of two additional inositol tetrakisphosphate (InsP4) isomers
D J Gawler et al.
The Biochemical journal, 276 ( Pt 1), 163-167 (1991-05-15)
The potential Ca2(+)-releasing activity of the inositol tetrakisphosphates Ins(1,3,4,6)P4 and DL-Ins(1,4,5,6)P4 and the inositol pentakisphosphate Ins(1,3,4,5,6)P5 and their effect on Ins(1,4,5)P3- and DL-Ins (1,3,4,5)P4-mediated Ca2+ release were examined in permeabilized SH-SY5Y human neuroblastoma cells. Neither DL-Ins(1,4,5,6)P4 nor Ins(1,3,4,5,6)P5 exhibit Ca2(+)-releasing
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