K1013
Kuanoniamine C from Oceanappia sp.
97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C21H18N4OS
CAS Number:
Molecular Weight:
374.46
MDL number:
UNSPSC Code:
12352202
Assay
97% (HPLC)
storage temp.
−20°C
SMILES string
CCCNCCc1cccc2c3ccnc4c5ncsc5cc([nH]c12)c34
Biochem/physiol Actions
Inhibits proliferation of select cell types; binds to adenosine receptor subtypes A1 and A2A.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Q Ding et al.
Current medicinal chemistry, 6(1), 1-27 (1999-01-05)
Marine organisms are a rich source for natural products. Pyrrolo[4,3, 2-de]quinolines and pyrido[4,3,2-mn]acridines are of major interest as metabolites in sponges and ascidians. Many of these compounds have generated interest both as challenging problems for structure elucidation and synthesis as
C Eder et al.
Journal of natural products, 61(2), 301-305 (1998-03-26)
The Micronesian sponge Oceanapia sp. afforded three pyridoacridine alkaloids: the known compounds kuanoniamine C (1) and kuanoniamine D (2), as well as the new N-deacyl derivative (3) of the kuanoniamines. Compounds 1 and 2 exhibited insecticidal activity toward neonate larvae
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