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Merck
CN

K4252

Sigma-Aldrich

Anti-Keratin antibody produced in guinea pig

whole antiserum

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

guinea pig

conjugate

unconjugated

antibody form

whole antiserum

clone

polyclonal

contains

15 mM sodium azide

species reactivity

bovine, human

technique(s)

indirect immunofluorescence: 1:20 using formalin-fixed, paraffin-embedded sections of human skin and bovine muzzle tissue

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... KRT1(3848)

Immunogen

keratin from fetal bovine hooves.

Biochem/physiol Actions

The antibody specifically labels networks of tonofilaments within epithelial cells in culture and in tissue sections.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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H N Antoniades et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(12), 5371-5375 (1992-06-15)
Macrophages are thought to play an important role in the pathologic changes associated with idiopathic pulmonary fibrosis (IPF). The mechanisms for increased monocyte/macrophage recruitment in IPF are unknown. Monocyte chemoattractant protein 1 (MCP-1) is the predominant monocyte chemoattractant secreted by
Annette Hansson et al.
European journal of oral sciences, 111(1), 34-41 (2003-02-01)
The current study was undertaken to analyse growth and differentiation-related functions of normal keratinocytes (NOK) and an SV40T-immortalized keratinocyte line (SVpgC2a) from buccal mucosa, viewing the latter cell line as a model of a dysplastic epithelium. Morphological and immunohistochemical assessments
A Y Alexandrova et al.
Cell motility and the cytoskeleton, 39(2), 147-158 (1998-03-04)
The effects of scatter factor, HGF/SF, on multinuclear MDCK epitheliocytes were examined. Multinuclear cells were obtained by blocking cytokinesis by low concentration of cytochalasin D; these large cells had discoid shape and did not move much on the substrate. Incubation
Cristina Risco et al.
Journal of virology, 76(4), 1839-1855 (2002-01-19)
Vaccinia virus (VV) has a complex morphogenetic pathway whose first steps are poorly characterized. We have studied the early phase of VV assembly, when viral factories and spherical immature viruses (IVs) form in the cytoplasm of the infected cell. After

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