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K4763

Anti-Ku70 antibody produced in rabbit

Name: Anti-Ku70 antibody produced in rabbit
Brand: SIGMA

affinity isolated antibody, ammonium sulfate suspension

Synonym(s):

Anti-G22P1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01633569

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

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biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

ammonium sulfate suspension

mol wt

antigen 69.8 kDa

species reactivity

human, rodent

technique(s)

immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

P12956

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... XRCC6(2547)
mouse ... Xrcc6(14375)
rat ... Xrcc6(25019)

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Immunogen

synthetic peptide corresponding to human Ku70 (amino acids 536-550) conjugated to BSA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

093K1267

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Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage.

Erika Koltai et al.

Rejuvenation research, 14(6), 585-596 (2011-08-27)

We have investigated the effects of 2 weeks of insulin-like growth factor-1 (IGF-1) supplementation (5 μg/kg per day) and 6 weeks of exercise training (60% of the maximal oxygen consumption [VO₂ max]) on neurogenesis, DNA damage/repair, and sirtuin content in

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.

Praveen Rajendran et al.

Epigenetics, 8(6), 612-623 (2013-06-19)

Histone deacetylases (HDACs) and acetyltransferases have important roles in the regulation of protein acetylation, chromatin dynamics and the DNA damage response. Here, we show in human colon cancer cells that dietary isothiocyanates (ITCs) inhibit HDAC activity and increase HDAC protein

Global Trade Item Number

SKU	GTIN
K4763-100UG	04061837772221

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