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Merck
CN

L0396

Leukotriene F4

~50 μg/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH, ~97%

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About This Item

Empirical Formula (Hill Notation):
C28H44N2O8S
CAS Number:
Molecular Weight:
568.72
UNSPSC Code:
12352200
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assay

~97%

concentration

~50 μg/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH

shipped in

dry ice

storage temp.

−20°C

Packaging

Packaged under Argon.

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Pallu Reddanna et al.
Archives of biochemistry and biophysics, 413(2), 158-163 (2003-05-06)
Leukotrienes (LTs) are 5-lipoxygenase (5-LO)-derived arachidonic metabolites that constitute a potent set of lipid mediators produced by inflammatory cells. Leukotriene A(4), a labile allylic epoxide formed from arachidonic acid by dual 5-LO activity, is the precursor for LTB(4) and LTC(4)
W M Abraham et al.
Prostaglandins, 31(3), 457-467 (1986-03-01)
Leukotriene (LT) D4 is a putative mediator of allergic asthma: inhaled LTD4 produces early and late increases in specific lung resistance (SRL) and slows tracheal mucus velocity (TMV) similar to inhaled antigen. In this study we examined the effects of
Leukotrienes as mediators of skin inflammation.
A W Ford-Hutchinson et al.
The British journal of dermatology, 109 Suppl 25, 26-29 (1983-07-01)
A novel leukotriene formed by transpeptidation of leukotriene E.
K Bernström et al.
Biochemical and biophysical research communications, 109(3), 800-804 (1982-12-15)
C C Chan et al.
The Journal of investigative dermatology, 84(2), 154-157 (1985-02-01)
The local effects of synthetic leukotrienes (LT) were examined in the skin of the anesthetized pig. Blood flow was measured noninvasively with the use of a laser-Doppler flow meter and changes in vascular permeability were measured using technetium-labeled human serum

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