L2136
Lauric acid N,N-dimethylamide
~95%
Synonym(s):
N,N-Dimethyldodecanamide, N,N-Dimethyllauramide
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About This Item
Empirical Formula (Hill Notation):
C14H29NO
CAS Number:
Molecular Weight:
227.39
UNSPSC Code:
12352211
PubChem Substance ID:
EC Number:
221-117-5
MDL number:
InChI key
BDYUSDIJIDGWCY-UHFFFAOYSA-N
InChI
1S/C14H29NO/c1-4-5-6-7-8-9-10-11-12-13-14(16)15(2)3/h4-13H2,1-3H3
SMILES string
CCCCCCCCCCCC(=O)N(C)C
assay
~95%
form
liquid
density
0.87 g/mL at 25 °C (lit.)
functional group
amide
shipped in
ambient
storage temp.
room temp
Application
Dermal penetration enhancer; facilitates transport of solutes through the skin.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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B B Michniak et al.
Journal of pharmaceutical sciences, 82(2), 214-219 (1993-02-01)
A series of novel dermal penetration enhancers, esters and amides of clofibric acid, was synthesized. The permeation parameters and skin retention of two steroids (hydrocortisone-21-acetate and betamethasone-17-valerate) in propylene glycol were studied with athymic nude mouse skin by in vitro
Kuo-Yen Huang et al.
EMBO molecular medicine, 13(1), e12828-e12828 (2020-11-08)
To circumvent the devastating pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, a humanized decoy antibody (ACE2-Fc fusion protein) was designed to target the interaction between viral spike protein and its cellular receptor, angiotensin-converting enzyme 2 (ACE2).
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