L2776
Lys-Gln-Ala-Gly-Asp-Val
≥97% (HPLC)
Synonym(s):
KQAGDV
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About This Item
Empirical Formula (Hill Notation):
C25H44N8O10
CAS Number:
Molecular Weight:
616.66
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥97% (HPLC)
form
powder
technique(s)
LC/MS: suitable
color
white to off-white
storage temp.
−20°C
SMILES string
CC(C)C(NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(N)CCCCN)C(O)=O
InChI
1S/C25H44N8O10/c1-12(2)20(25(42)43)33-24(41)16(10-19(36)37)31-18(35)11-29-21(38)13(3)30-23(40)15(7-8-17(28)34)32-22(39)14(27)6-4-5-9-26/h12-16,20H,4-11,26-27H2,1-3H3,(H2,28,34)(H,29,38)(H,30,40)(H,31,35)(H,32,39)(H,33,41)(H,36,37)(H,42,43)
InChI key
AFAFFVKJJYBBTC-UHFFFAOYSA-N
Biochem/physiol Actions
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide used to study adhesion of platelets to neutrophils via the integrin glycoproteins gpIIb/IIIa.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Bernard Chabannes et al.
British journal of haematology, 121(2), 341-348 (2003-04-16)
Polymorphonuclear leucocytes and blood platelets co-operate in several pathophysiological processes, and arachidonic acid (AA) metabolites produced in response to the activation of these cells are potent mediators of their functions. We studied the role of platelets in the formation of
Brenda K Mann et al.
Journal of biomedical materials research, 60(1), 86-93 (2002-02-09)
The effects of cell adhesion peptides (RGDS, KQAGDV, VAPG) on vascular smooth muscle cells grown on modified surfaces and in tissue-engineering scaffolds were examined. Cells were more strongly adhered to surfaces modified with adhesive ligands than to control surfaces (no
Integrins.
E Ruoslahti
The Journal of clinical investigation, 87(1), 1-5 (1991-01-01)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L2776-1MG | 04061826284872 |