L2917
Anti-phospho-Lck (pSer158) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
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About This Item
UNSPSC Code:
12352203
MDL number:
antibody form
affinity isolated antibody
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: 0.1-1.0 μg/mL using full length recombinant human Lck protein.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... LCK(3932)
mouse ... Lck(16818)
Immunogen
synthetic phosphopeptide derived from the region of Lck that is phosphorylated on serine 158. Mouse and human have 100% homology.
Physical form
Solution in phosphate buffer, pH 7.4, containing 1 mg/mL BSA (IgG and protease free) and 0.05% sodium azide.
Preparation Note
The antibody is preadsorbed to remove any reactivity towards a non-phosphorylated Lck.
Regulatory Information
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W Fujimaki et al.
The Journal of biological chemistry, 276(20), 17455-17460 (2001-03-30)
Human thymic CD1a-CD4+ T cells in the final stage of thymic maturation are susceptible to anergy induced by a superantigen, toxic shock syndrome toxin-1 (TSST-1). Thymic CD4+ T-cell blasts, established by stimulating human thymic CD1a-CD4+ T cells with TSST-1 in
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