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L3276

Monoclonal Anti-LEF-1 antibody produced in mouse

Name: Monoclonal Anti-LEF-1 antibody produced in mouse
Brand: SIGMA

~1 mg/mL, clone 1C3, purified immunoglobulin

Synonym(s):

Anti-Lymphoid Enhancer Factor-1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03457562

Conjugate:

unconjugated

Clone:

1C3, monoclonal

Application:

Citations:

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biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1C3, monoclonal

mol wt

antigen 55-57 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

western blot: 1-5 μg/mL using whole extracts of human Jurkat cells or transiently expressed human LEF-1 in whole cell lysates from Cos-1 cells

isotype

IgG1

UniProt accession no.

Q9UJU2

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LEF1(51176)

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Immunogen

recombinant full length LEF-1.

Physical form

Solution in 0.01 M phosphate buffered saline containing 0.08% sodium azide.

Preparation Note

Purified from cell culture supernatnant.

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Storage Class

10 - Combustible liquids

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

079K1267

120K0161

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Canonical WNT Signaling Pathway is Altered in Mesenchymal Stromal Cells From Acute Myeloid Leukemia Patients And Is Implicated in BMP4 Down-Regulation.

Pedro L Azevedo et al.

Translational oncology, 12(4), 614-625 (2019-02-01)

Mesenchymal stromal cells (hMSCs) are key components of the bone marrow microenvironment (BMM). A molecular signature in hMSCs from Acute myeloid leukemia patients (hMSC-AML) has been proposed where BMP4 is decreased and could be regulated by WNT signaling pathway. Therefore

Global Trade Item Number

SKU	GTIN
L3276-.1MG	04061836275884

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