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Merck
CN

L3523

Sigma-Aldrich

[Trp4]-Kemptide

≥97% (HPLC)

Synonym(s):

Leu-Arg-Arg-Trp-Ser-Leu-Gly

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About This Item

Empirical Formula (Hill Notation):
C40H66N14O9
CAS Number:
Molecular Weight:
887.04
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)CC(N)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NCC(O)=O

General description

Substrate for cAMP-dependent protein kinase and phosphoprotein phosphatase; peptide fluorescence intensity changes as a function of its phosphorylation state.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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D E Wright et al.
Proceedings of the National Academy of Sciences of the United States of America, 78(10), 6048-6050 (1981-10-01)
A novel peptide substrate for adenosine 3',5'-cyclic monophosphate-dependent protein kinase (ATP:protein phosphotransferase, EC 2.7.1.37), Leu-Arg-Arg-Trp-Ser-Leu-Gly, was synthesized. Phosphorylation of the peptide causes a 20% increase in the peptide fluorescence intensity at 358 nm. Values of Km and kcat for the

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