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Merck
CN

L4283

Lithium carbonate

BioXtra, ~99%

Synonym(s):

Carbolithium, Carbonic acid lithium salt

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About This Item

Linear Formula:
Li2CO3
CAS Number:
Molecular Weight:
73.89
EC Number:
209-062-5
UNSPSC Code:
12352300
PubChem Substance ID:
Beilstein/REAXYS Number:
3999191
MDL number:
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InChI key

XGZVUEUWXADBQD-UHFFFAOYSA-L

InChI

1S/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2

SMILES string

[Li+].[Li+].[O-]C([O-])=O

product line

BioXtra

assay

~99%

impurities

≤0.01% Phosphorus (P), ≤0.1% Insoluble matter

mp

618 °C (lit.)

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%, Ca: ≤0.002%, Cu: ≤0.0005%, Fe: ≤0.003%, K: ≤0.01%, Mg: ≤0.01%, NH4+: ≤0.05%, Na: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005%

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signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Andrea Contestabile et al.
The Journal of clinical investigation, 123(1), 348-361 (2012-12-04)
Down syndrome (DS) patients exhibit abnormalities of hippocampal-dependent explicit memory, a feature that is replicated in relevant mouse models of the disease. Adult hippocampal neurogenesis, which is impaired in DS and other neuropsychiatric diseases, plays a key role in hippocampal
Tom Bschor et al.
Journal of clinical psychopharmacology, 33(1), 38-44 (2013-01-02)
Studies of the 1970s and 1980s showed lithium monotherapy to be an effective treatment of acute unipolar major depressive disorder (MDD) and hence as a potential alternative to monoaminergic antidepressants.The objective was to conduct the first comparison of a lithium
Andrew A Nierenberg et al.
The American journal of psychiatry, 170(1), 102-110 (2013-01-05)
Lithium salts, once the mainstay of therapy for bipolar disorder, have tolerability issues at a higher dosage that often limit adherence. The authors investigated the comparative effectiveness of more tolerable dosages of lithium as part of optimized personalized treatment (OPT).
M Simard et al.
Archives of internal medicine, 149(1), 36-46 (1989-01-01)
Lithium carbonate is a widely used and invaluable drug in the treatment and prevention of manic-depressive illness. However, this medication has a low therapeutic index and, therefore, many attendant side effects. Acute lithium carbonate intoxication affects predominantly the central nervous
R Yassa et al.
International pharmacopsychiatry, 15(5), 301-308 (1980-01-01)
In this paper, the efficacy of lithium therapy in the treatment of tardive dyskinesia is reviewed. It is noted that most of the published papers on this topic are anecdotal and single case reports with contradictory results. The well-designed studies

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