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Merck
CN

L4376

α-Lobeline hydrochloride

~95% (HPLC), powder

Synonym(s):

2-[6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenylethanone hydrochloride, (−)-Lobeline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H27NO2 · HCl
CAS Number:
134-63-4
Molecular Weight:
373.92
UNSPSC Code:
12352200
EC Number:
205-150-2
Beilstein/REAXYS Number:
3920196
MDL number:
MFCD00082455

Key Documents

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SMILES string

Cl.CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@H](O)c3ccccc3

assay

~95% (HPLC)

form

powder

color

white to off-white

solubility

H2O: 25 mg/mL

Gene Information

human ... SLC18A2(6571)

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Biochem/physiol Actions

Agonist at high-affinity neuronal nicotinic acetylcholine receptors; respiratory stimulant. Inhibits synaptosomal accumulation of dopamine by interaction with the tetrabenazine binding site of the vesicular monoamine transporter (VMAT2). Blocks amphetamine-induced dopamine release.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

新产品
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Certificates of Analysis (COA)

Lot/Batch Number
074H7711
025H0088
118H1325
098F0033
086H1204

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