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Merck
CN

L5629

1-Dodecanoyl-sn-glycero-3-phosphocholine

~99%

Synonym(s):

L-α-Lysophosphatidylcholine, lauroyl, Lysolecithin, lauroyl

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About This Item

Empirical Formula (Hill Notation):
C20H42NO7P
CAS Number:
Molecular Weight:
439.52
UNSPSC Code:
12352211
PubChem Substance ID:
MDL number:
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InChI

1S/C20H43NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3,(H,24,25)

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O

InChI key

HFADNALDARCBSD-UHFFFAOYSA-N

description

zwitterionic

assay

~99%

mol wt

439.52 g/mol

functional group

ester

shipped in

ambient

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Peng Lin et al.
Peptides, 28(8), 1514-1519 (2007-08-21)
An antifungal peptide with a molecular mass of 9412 and an N-terminal sequence exhibiting notable homology to those of lipid transfer proteins was isolated from seeds of the vegetable Brassica campestris. The purification protocol entailed ion exchange chromatography on Q-Sepharose
The polar group conformation of a lysophosphatidylcholine analogue in solution. A high-resolution nuclear magnetic resonance study.
H Hauser et al.
Journal of molecular biology, 137(3), 265-282 (1980-03-05)
A Gow et al.
Biochemistry, 29(5), 1142-1147 (1990-02-06)
The binding of myelin basic protein to lysolauroylphosphatidylcholine (lysoLPC) and lysolauroylphosphatidylethanolamine was investigated at neutral pH using gel partition chromatography and equilibrium dialysis at 20 and 37 degrees C. The results show that the protein-lysolipid interactions are highly cooperative and
R H Notter et al.
Journal of applied physiology: respiratory, environmental and exercise physiology, 57(6), 1613-1624 (1984-12-01)
Pulmonary surfactant research is considered from the perspective of interdisciplinary correlations based on information acquired from biophysics and physical chemistry, biochemistry, cell biology, physiology, and medicine. Current views of the important molecular constituents of the pulmonary surfactant system are described
Conformation of phospholipids. Crystal structure of a lysophosphatidylcholine analogue.
H Hauser et al.
Journal of molecular biology, 137(3), 249-264 (1980-03-05)

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