L6004
Lincomycin hydrochloride
≥90% (TLC)
Synonym(s):
Epilincomycin, Lincomycin HCL, Lincocin hydrochloride, Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride
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About This Item
Quality Segment
assay
≥90% (TLC)
potency
800-900 units per mg
color
white to faint yellow
solubility
H2O: soluble 50 mg/mL
antibiotic activity spectrum
Gram-positive bacteria
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
InChI
1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1
InChI key
POUMFISTNHIPTI-BOMBIWCESA-N
General description
Application
Biochem/physiol Actions
Antimicrobial spectrum: Lincomycin hydrochloride is effective against gram-positive bacteria.
Preparation Note
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Articles
Antibiotics targeting bacterial ribosomes disrupt protein synthesis, a key process in bacterial growth inhibition.
蛋白质合成是一个复杂、多步骤过程，涉及到很多酶以及构象排列。但是，阻碍细菌蛋白质合成的大部分抗生素对该过程的干扰发生在70S细菌核糖体的30S亚基或50S亚基。
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L6004-1MU | 04061833958551 |
| L6004-25MU | 04061833622476 |
| L6004-5MU | 04061833611791 |