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Merck
CN

L6401

Sigma-Aldrich

Lacto-N-fucopentaose II

from human milk, ≥98% (HPAE/PAD)

Synonym(s):

β-D-Gal-(1→3)-(α-L-Fuc-[1→4])-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNFP II, Lea-Lactose, Lewis-a pentasaccharide

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About This Item

Empirical Formula (Hill Notation):
C32H55NO25
CAS Number:
21973-23-9
Molecular Weight:
853.77
Beilstein:
6050703
MDL number:
MFCD00171398
UNSPSC Code:
12352200

Key Documents

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biological source

human milk

Assay

≥98% (HPAE/PAD)

storage temp.

2-8°C

SMILES string

C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(C)=O)[C@@H](O[C@@H]2CO)O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]4[C@@H](CO)OC(O)[C@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)[C@@H]3O)[C@@H](O)[C@H](O)[C@@H]1O

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
030K3789
022K3791
093K1428

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R W Loveless et al.
The Biochemical journal, 258(1), 109-113 (1989-02-15)
Carbohydrate recognition by bovine serum conglutinin has been investigated by inhibition and direct binding assays using glycoproteins and polysaccharides from Saccharomyces cerevisiae (baker's yeast), and neoglycolipids derived from N-acetylglucosamine oligomers, mannobiose and human milk oligosaccharides. The results clearly show that
J Alexander et al.
Journal of immunology (Baltimore, Md. : 1950), 164(3), 1625-1633 (2000-01-21)
Linear carbohydrate-peptide constructs based on the 13 amino acid nonnatural pan DR epitope (PADRE) and carbohydrate B cell epitopes are demonstrated to be potent immunogens. These data support our belief that PADRE should be considered as an alternative to more
T Solouki et al.
Analytical chemistry, 70(5), 857-864 (1998-03-25)
Mass spectra of fragments of permethylated oligosaccharides are analyzed by Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. Sustained off-resonance irradiation (SORI) collision-induced dissociation (CID), quadrupolar axialization, multiple stages of isolation and dissociation (MSn), and ion remeasurement are exploited for
Carbohydrate differentiation and cancer-associated antigens detected by monoclonal antibodies.
J L Magnani
Biochemical Society transactions, 12(3), 543-545 (1984-06-01)
Elin Säwén et al.
Organic & biomolecular chemistry, 10(23), 4577-4585 (2012-05-11)
Human milk oligosaccharides (HMOs) are important as prebiotics since they stimulate the growth of beneficial bacteria in the intestine and act as receptor analogues that can inhibit the binding of pathogens. The conformation and dynamics of the HMO Lacto-N-fucopentaose 2
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