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Merck
CN

L6401

Lacto-N-fucopentaose II

from human milk, ≥98% (HPAE/PAD)

Synonym(s):

β-D-Gal-(1→3)-(α-L-Fuc-[1→4])-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNFP II, Lea-Lactose, Lewis-a pentasaccharide

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About This Item

Empirical Formula (Hill Notation):
C32H55NO25
CAS Number:
21973-23-9
Molecular Weight:
853.77
UNSPSC Code:
12352200
MDL number:
MFCD00171398
Beilstein/REAXYS Number:
6050703

Key Documents

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SMILES string

C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(C)=O)[C@@H](O[C@@H]2CO)O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]4[C@@H](CO)OC(O)[C@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)[C@@H]3O)[C@@H](O)[C@H](O)[C@@H]1O

biological source

human milk

assay

≥98% (HPAE/PAD)

storage temp.

2-8°C

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
030K3789
022K3791
093K1428

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M Larkin et al.
The Journal of biological chemistry, 267(19), 13661-13668 (1992-07-05)
Carbohydrate recognition by the human endothelial-leukocyte adhesion molecule, E-selectin, has been investigated by binding studies using 3H-labeled Chinese hamster ovary cells expressing different levels of the transfected full-length adhesion molecule and a series of structurally defined oligosaccharides linked to the
Elin Säwén et al.
Organic & biomolecular chemistry, 10(23), 4577-4585 (2012-05-11)
Human milk oligosaccharides (HMOs) are important as prebiotics since they stimulate the growth of beneficial bacteria in the intestine and act as receptor analogues that can inhibit the binding of pathogens. The conformation and dynamics of the HMO Lacto-N-fucopentaose 2
Carbohydrate differentiation and cancer-associated antigens detected by monoclonal antibodies.
J L Magnani
Biochemical Society transactions, 12(3), 543-545 (1984-06-01)
T Solouki et al.
Analytical chemistry, 70(5), 857-864 (1998-03-25)
Mass spectra of fragments of permethylated oligosaccharides are analyzed by Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. Sustained off-resonance irradiation (SORI) collision-induced dissociation (CID), quadrupolar axialization, multiple stages of isolation and dissociation (MSn), and ion remeasurement are exploited for
Alexander Pirkl et al.
Analytical chemistry, 84(13), 5669-5676 (2012-06-08)
Although water ice has been utilized in the past as a matrix for infrared matrix-assisted laser desorption/ionization mass spectrometry (IR-MALDI-MS), it has not found a wider use due to limitations in the analytical performance and technical demands on the employment
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