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Merck
CN

L6543

Lacto-N-neo-tetraose

synthetic, ≥85% (HPLC)

Synonym(s):

β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNnT

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About This Item

Empirical Formula (Hill Notation):
C26H45NO21
CAS Number:
Molecular Weight:
707.63
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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biological source

synthetic

assay

≥85% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

CC(=O)NC1C(O)C(OC2OC(CO)C(O)C(O)C2O)C(CO)OC1OC3C(O)C(CO)OC(OC(C(O)CO)C(O)C(O)C=O)C3O

InChI

1S/C26H45NO21/c1-7(33)27-13-17(39)22(47-25-19(41)18(40)15(37)10(4-30)43-25)12(6-32)45-24(13)48-23-16(38)11(5-31)44-26(20(23)42)46-21(9(35)3-29)14(36)8(34)2-28/h2,8-26,29-32,34-42H,3-6H2,1H3,(H,27,33)

InChI key

RBMYDHMFFAVMMM-UHFFFAOYSA-N



Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上,并可占总量的50-80%。


Julie Elisabeth Heggelund et al.
International journal of molecular sciences, 20(3) (2019-02-10)
Diarrhea caused by enterotoxigenic Escherichia coli (ETEC) is one of the leading causes of mortality in children under five years of age and is a great burden on developing countries. The major virulence factor of the bacterium is the heat-labile
Liana Steeghs et al.
Cellular microbiology, 8(2), 316-325 (2006-01-31)
Neisseria meningitidis lipopolysaccharide (LPS) has been identified as a major determinant of dendritic cell (DC) function. Here we report that one of a series of meningococcal mutants with defined truncations in the lacto-N-neotetraose outer core of the LPS exhibited unique
M P Jennings et al.
Microbiology (Reading, England), 145 ( Pt 11), 3013-3021 (1999-12-10)
Neisseria meningitidis strains express a diverse range of lipopolysaccharide (LPS) structures that have been classified into 12 immunotypes. A feature of meningococcal LPS is the reversible, high-frequency switching of expression (phase variation) of terminal LPS structures. A number of studies