L7271
Leukotriene C4 methyl ester
~50 μg/mL in methanol: water (7:3) containing ammonium acetate buffer (≤0.1%), pH 5.4, ~97%
Assay
~97%
concentration
~50 μg/mL in methanol: water (7:3) containing ammonium acetate buffer (≤0.1%), pH 5.4
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Methyl ester form of Leukotriene C4 which induces bronchoconstriction and renal vasoconstriction.
Packaging
Packaged under Argon.
Regulatory Information
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S V Galushko et al.
Bioorganicheskaia khimiia, 15(7), 952-959 (1989-07-01)
The chromatographic (RP HPLC) behaviour of leukotriene C4, its methyl ester, leukotriene A4 methyl ester and some chemicals involved in their synthesis have been investigated. Optimal conditions of separation were determined for the gradient and isocratic HPLC. Parameters of the
R Agarwal et al.
Biochemical pharmacology, 44(10), 2047-2053 (1992-11-17)
The glutathione S-transferase (GST)-dependent conjugation of reduced glutathione (GSH) with leukotriene A4 (LTA4)-methyl ester in rodent and human skin was investigated. Incubation of [3H]LTA4-methyl ester (1 nmole, approximately 200,000 dpm) with cytosol prepared from rat, mouse and human skin or
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