L9125
L-Leucine-p-nitroanilide
leucine aminopeptidase substrate, chromogenic, ≥98% (TLC), powder
Synonym(s):
L-Leucine-4-nitroanilide
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C12H17N3O3
CAS Number:
Molecular Weight:
251.28
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
224-047-3
MDL number:
Beilstein/REAXYS Number:
2218433
Product Name
L-Leucine-p-nitroanilide, leucine aminopeptidase substrate
InChI
1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1
SMILES string
CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI key
AXZJHDNQDSVIDR-NSHDSACASA-N
assay
≥98% (TLC)
form
powder
solubility
ethanol: 50 mg/mL
storage temp.
2-8°C
Quality Level
General description
Substrate for the colorimetric determination of leucine aminopeptidase.
Application
L-Leucine-p-nitroanilide has been used as substrate
- for the determination of intestinal leucine aminopeptidase activity of juvenile rainbow trout (Oncorhynchus mykiss)
- in insulin-regulated aminopeptidase inhibition assay
- for determining exopeptidase activity
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Effects of fish meal replacement with meat and bone meal using garlic (Allium sativum) powder on growth, feeding, digestive enzymes and apparent digestibility of nutrients and fatty acids in juvenile rainbow trout (Oncorhynchus mykiss Walbaum, 1792)
Esmaeili M, et al.
Aquaculture Nutrition, 23(6), 1225-1234 (2017)
A Bernkop-Schnürch et al.
Pharmaceutical research, 14(2), 181-185 (1997-02-01)
Develop and evaluate systems to prevent aminopeptidase N caused enzymatic degradation of perorally administrated peptide drugs. Bacitracin was covalently bound to the unabsorbable carrier matrix poly(acrylic acid) (paa) in order to avoid any dilution effects of the inhibitor in the
W Bawab et al.
The Biochemical journal, 286 ( Pt 3), 967-975 (1992-09-15)
Aminopeptidase activities were identified in extracts of kidney, ovotestis, head ganglia, heart and haemolymph of Aplysia californica. These enzyme preparations hydrolysed [3H][Leu]enkephalin at the Try-1-Gly-2 bond as determined by h.p.l.c. analysis of cleavage products. In all these tissues, enkephalin-degrading aminopeptidase
Identification of drug-like inhibitors of insulin-regulated aminopeptidase through small-molecule screening
Engen K, et al.
Assay and Drug Development Technologies, 14(3), 180-193 (2016)
Pablo Emiliano Cantón et al.
Frontiers in physiology, 10, 1553-1553 (2020-01-24)
Nezara viridula is a polyphagous stink bug that feeds on crops of economic importance such as corn, soybean and cotton. To increase understanding of the ability of this pest insect to feed on such diverse cropping systems, we analyzed the
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service