Skip to Content
Merck
CN

L9788

Lymphotactin human

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Synonym(s):

ATAC, Lptn, SCM-1α, XCLI

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
51111800
MDL number:
MFCD01094238

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

human

recombinant

expressed in E. coli

assay

>97% (SDS-PAGE)

form

lyophilized powder

potency

0.05-0.2 μg/mL ED50 (for chemotaxis of BaF/3 hCXR1 cells), 6-12 μg/mL ED50 (for chemotaxis of IL-2 cultured lymphocytes)

mol wt

predicted mol wt 10.4 kDa

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

impurities

endotoxin, tested

UniProt accession no.

P47992

storage temp.

−20°C

Gene Information

human ... XCL1(6375)

Biochem/physiol Actions

Lymphotactin (Lptn), a member of the C or γ subfamily of chemokines, is similar to members of the CC and CXC chemokine families, but lacks two of the four cysteine residues. Recombinant mouse lymphotactin has chemotactic activity for lymphocytes, NK cells, and mouse splenocytes, but not for monocytes or neutrophils.
Member of the C or γ subfamily of chemokines, is similar to members of the CC and CXC chemokine families, but lacks two of the four cysteine residues.

Physical form

Lyophilized from a 0.2 μm filtered solution 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to chemoattract mouse BaF/3 cells transfected with hXCR1.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLBF6778V
101K0323

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lymphotactin: a new class of chemokine.
J A Hedrick et al.
Methods in enzymology, 287, 206-215 (1997-01-01)
Annabell Bachem et al.
The Journal of experimental medicine, 207(6), 1273-1281 (2010-05-19)
In recent years, human dendritic cells (DCs) could be subdivided into CD304+ plasmacytoid DCs (pDCs) and conventional DCs (cDCs), the latter encompassing the CD1c+, CD16+, and CD141+ DC subsets. To date, the low frequency of these DCs in human blood
Christina Guzzo et al.
PLoS pathogens, 9(12), e1003852-e1003852 (2014-01-05)
CD8+ T cells play a key role in the in vivo control of HIV-1 replication via their cytolytic activity as well as their ability to secrete non-lytic soluble suppressive factors. Although the chemokines that naturally bind CCR5 (CCL3/MIP-1α, CCL4/MIP- 1β
G S Kelner et al.
Science (New York, N.Y.), 266(5189), 1395-1399 (1994-11-25)
In this study, the cytokine-producing profile of progenitor T cells (pro-T cells) was determined. During screening of a complementary DNA library generated from activated mouse pro-T cells, a cytokine designated lymphotactin was discovered. Lymphotactin is similar to members of both

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service