M118
(−)-Methoxyverapamil hydrochloride
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C28H40N2O5 · HCl
CAS Number:
Molecular Weight:
521.09
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
Cl[H].COc1ccc(CCN(C)CCC[C@@](C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC
optical activity
[α]26/D −11.7°, c = 5.04 in ethanol(lit.)
solubility
H2O: soluble
Biochem/physiol Actions
Ca2+ channel (L-type) antagonist; active enantiomer of methoxyverapamil.
Disclaimer
Photosensitive
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Drug action and cellular calcium regulation.
Janis, P.R., et al. et al.
Advances in Drug Research, 16, 309-309 (1987)
J A Wagner et al.
Journal of cardiovascular pharmacology, 10 Suppl 10, S1-S9 (1987-01-01)
We studied voltage-sensitive and Na-dependent Ca2+ flux into synaptosomes as well as Na-dependent influx in cardiac sarcolemmal vesicles. Rapid, voltage-sensitive 45Ca2+ influx into synaptosomes is blocked by cadmium (IC50 1 microM) and the novel peptide toxin omega-conotoxin GVIA (30% of
G B Frank
The Journal of pharmacology and experimental therapeutics, 236(2), 505-511 (1986-02-01)
Contractures of the toe muscles of frogs produced by 123 mM K+ were reduced or blocked by verapamil (or D-600) when applied in concentrations of 10(-7) M or more. In concentrations between 10(-7) and 3 X 10(-5) M or less
Maria Trott et al.
PloS one, 9(5), e97478-e97478 (2014-05-16)
HIV neutralizing antibodies (nAbs) represent an important tool in view of prophylactic and therapeutic applications for HIV-1 infection. Patients chronically infected by HIV-1 represent a valuable source for nAbs. HIV controllers, including long-term non-progressors (LTNP) and elite controllers (EC), represent
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service