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Merck
CN

M1189

Supelco

Methiazole

98% (TLC)

Synonym(s):

Methyl 5-(isopropylthio)benzimidazole-2-carbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O2S
Molecular Weight:
265.33
MDL number:
MFCD11044449
UNSPSC Code:
41116107
PubChem Substance ID:
24896624

Key Documents

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Assay

98% (TLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

COC(=O)Nc1nc2cc(SC(C)C)ccc2[nH]1

InChI

1S/C12H15N3O2S/c1-7(2)18-8-4-5-9-10(6-8)14-11(13-9)15-12(16)17-3/h4-7H,1-3H3,(H2,13,14,15,16)

InChI key

SXJIZQPZESTWLD-UHFFFAOYSA-N

General description

Broad spectrum anthelmintic with efficiency equal to albendazole. Efficient in cases of polyinvasion, especially against Echinococcus.
White crystalline powder, sometimes grey-shaded.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品
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Certificates of Analysis (COA)

Lot/Batch Number
078K1545
081K1318

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Iwao Shimomura et al.
Cancer letters, 451, 11-22 (2019-03-14)
KRAS is one of the most frequently mutated oncogenes in human non-small cell lung cancer (NSCLC). Mutations in KRAS are detected in 30% of NSCLC cases, with most of them occurring in codons 12 and 13 and less commonly in

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