M1256
6-Methylpurine riboside
Synonym(s):
6-Methyl-9-(1-β-D-ribofuranosyl)purine
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About This Item
Empirical Formula (Hill Notation):
C11H14N4O4
CAS Number:
Molecular Weight:
266.25
UNSPSC Code:
12352204
PubChem Substance ID:
storage temp.
−20°C
InChI
1S/C11H14N4O4/c1-5-7-10(13-3-12-5)15(4-14-7)11-9(18)8(17)6(2-16)19-11/h3-4,6,8-9,11,16-18H,2H2,1H3
InChI key
FIGBCBGMUIGJBD-UHFFFAOYSA-N
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M D Thompson et al.
Journal of medicinal chemistry, 40(5), 766-770 (1997-02-28)
A series of 2,4,6-trisubstituted-5-nitropyrimidines have been prepared and evaluated for inhibition of proliferation of L1210 and H.Ep.2 cells in vitro. The most potent compound was 6-(dibromomethyl)-2-methoxy-4-morpholino-5-nitropyrimidine (11) (L1210, IC50 = 0.32 microM; H.Ep.2, IC50 = 1.6 microM). Of the 6-substituents
Adenosine phosphorylase-mediated nucleoside toxicity. Application towards the detection of mycoplasmal infection in mammalian cell cultures.
G J McGarrity et al.
Experimental cell research, 139(1), 199-205 (1982-05-01)
K Leonhardt et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 42(4), 420-424 (1987-04-01)
6-Methylpurine, 6-methyl-9-beta-D-ribofuranosylpurine and 6-hydroxymethyl-9-beta-D-ribofuranosylpurine were isolated from mycelial cultures of Collybia maculata and their antifungal, cytotoxic and antiviral activities investigated. This is the first report on the natural occurrence of these compounds.