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Merck
CN

M183

Memantine hydrochloride

Synonym(s):

3,5-Dimethyl-1-adamantanamine hydrochloride, 3,5-Dimethylamantadine hydrochloride, 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H21N · HCl
CAS Number:
Molecular Weight:
215.76
EC Number:
255-219-6
UNSPSC Code:
41116107
MDL number:
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InChI key

LDDHMLJTFXJGPI-VXMZOEJHSA-N

InChI

1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H/t9-,10+,11-,12-;

SMILES string

Cl.C[C@]12CC3C[C@](C)(C1)CC(N)(C3)C2

format

neat

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Ramya Varatharajan et al.
Neurochemistry international, 90, 255-260 (2015-10-10)
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Progress in neuro-psychopharmacology & biological psychiatry, 54, 299-314 (2014-07-16)
A relevant role for dopamine-glutamate interaction has been reported in the pathophysiology and treatment of psychoses. Dopamine and glutamate may interact at multiple levels, including the glutamatergic postsynaptic density (PSD), an electron-dense thickening that has gained recent attention as a
Teresa A Barber et al.
Behavioural pharmacology, 26(4), 407-410 (2015-03-05)
Evidence of observational learning (social learning) is present in many species. One such task is the one-trial taste-avoidance task, in which Actor chicks peck a bead coated with an aversant substance. Observer chicks learn to avoid beads that are similar
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Neuropharmacology, 85, 384-396 (2014-06-08)
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Biochemical and biophysical research communications, 518(1), 161-170 (2019-08-23)
Chemical intervention of autophagy has been investigated in clinical trials for various age-related conditions such as sarcopenia and neurodegeneration. However, at present, no autophagy inducer has been established as a disease-modifying agent against neurodegenerative diseases. We screened a library consisting

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