M3152
Methoxypolyethylene glycol succinate N-hydroxysuccinimide
~50%, mol wt ~5,000
Synonym(s):
mono-Methyl polyethylene glycol succinate N-succinimidyl ester, O-Methyl-O′-succinylpolyethylene glycol 5,000 N-succinimidyl ester, PEG-succinimidyl succinate
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About This Item
mol wt
~5,000
concentration
~50%
storage temp.
−20°C
InChI
1S/C11H15NO7/c13-5-6-18-7-8(14)1-4-11(17)19-12-9(15)2-3-10(12)16/h13H,1-7H2
InChI key
OVPTZXRXNNJKSJ-UHFFFAOYSA-N
Application
For protein modification. May improve solubility and extend biological lifetime.
Other Notes
Shearwater Polymers product
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Georgi As Georgiev et al.
Colloids and surfaces. B, Biointerfaces, 59(2), 184-193 (2007-06-26)
Foam thin liquid films (TLF) and monolayers at the air-water interface formed by DMPC mixed with DMPE-bonded poly (ethylene glycol)s (DMPE-PEG(550), DMPE-PEG(2000) and DMPE-PEG(5000)) were obtained. The influence of both (i) PEG chain size (evaluated in terms of Mw) and
M A Croyle et al.
Journal of virology, 75(10), 4792-4801 (2001-04-20)
Most of the early gene therapy trials for cystic fibrosis have been with adenovirus vectors. First-generation viruses with E1a and E1b deleted are limited by transient expression of the transgene and substantial inflammatory responses. Gene transfer is also significantly curtailed
Y P Li et al.
Acta pharmacologica Sinica, 22(6), 549-555 (2001-12-19)
To assess the merits of polyethylene glycol-modified recombinant human tumor necrosis factor alpha (PEG-rHuTNF-alpha). The rHuTNF-alpha was modified with N-succinimidyl succinate monomethoxy polyethylene glycol (SS-PEG) of three different molecular weights. The PEG-rHuTNF-alpha was separated into fractions of various molecular weights