M3277
Methoxypolyethylene glycol activated with cyanuric chloride
average mol wt 5,000
mol wt
average mol wt 5,000
storage temp.
−20°C
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Application
Methoxypolyethylene glycol activated with cyanuric chloride has been used in a study to assess the biophysical consequences of linker chemistry and polymer size on stealth erythrocytes. It has also been used in a study to quantify dithiothreitol displacement of functional ligands from gold nanoparticles. This detergent is also for modification of proteins; it may improve solubility and extend biological lifetime.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Quantifying dithiothreitol displacement of functional ligands from gold nanoparticles
Tsai, D., et al.
Analytical and Bioanalytical Chemistry, 3015-3023 (2012)
C J Jackson et al.
Analytical biochemistry, 165(1), 114-127 (1987-08-15)
The experimental conditions for the preparation of conjugates of ovalbumin (OA) and monomethoxypolyethylene glycol (mPEG) of a preselected average degree of conjugation, n, using cyanuric chloride as the coupling agent, have been investigated with emphasis on purification and characterization of
A Abuchowski et al.
The Journal of biological chemistry, 252(11), 3578-3581 (1977-06-10)
Methoxypolyethylene glycols of 1900 and 5000 daltons have been attached covalently to bovine serum albumin using cyanuric chloride as the coupling agent. When sufficient polymer is attached, the modified bovine serum albumin appears to lose its immunogenicity in the rabbit
Amanda J Bradley et al.
Biochimica et biophysica acta, 1561(2), 147-158 (2002-05-09)
Immunocamouflaged red blood cells (RBC) are produced by cell surface derivatization with methoxypolyethylene glycol (mPEG). These immunologically attenuated cells may reduce the risk of allosensitization in chronically transfused patients. To characterize the effects of differing linker chemistries and polymer lengths
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