M3656
Mephentermine hemisulfate salt
Synonym(s):
N,α,α-Trimethylphenethylamine hemisulfate salt
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About This Item
Linear Formula:
C11H17N · 1/2H2SO4
CAS Number:
Molecular Weight:
212.30
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
214-923-3
MDL number:
SMILES string
OS(O)(=O)=O.CNC(C)(C)Cc1ccccc1.CNC(C)(C)Cc2ccccc2
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
Biochem/physiol Actions
α-adrenoceptor agonist.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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M A Mori et al.
Xenobiotica; the fate of foreign compounds in biological systems, 23(1), 11-18 (1993-01-01)
1. The N-demethylation of mephentermine (MP), p-hydroxymephentermine (p-hydroxy-MP) and N-hydroxymephentermine (N-hydroxy-MP), to produce phentermine (Ph), p-hydroxyphentermine (p-hydroxy-Ph) and N-hydroxyphentermine (N-hydroxy-Ph), and the p-hydroxylation of MP and Ph, to produce p-hydroxy-MP and p-hydroxy-Ph, were examined using rat liver microsomal preparations containing
Up-down study--is the analysis adequate?
J K Makkar et al.
Anaesthesia and intensive care, 38(1), 208-209 (2010-03-03)
B Bhattarai et al.
JNMA; journal of the Nepal Medical Association, 49(177), 23-28 (2010-12-25)
Hypotension is common following spinal anesthesia. Various vasopressors have been indicated to prevent it. The study compares three such agents namely phenylephrine, ephedrine and mephentermine. The study included 90 patients undergoing elective and emergency cesarean section who developed hypotension following
T Murali Krishna et al.
European journal of anaesthesiology, 25(4), 299-306 (2007-09-26)
Intrathecal ketamine produces a short period of analgesia with stable haemodynamics. Midazolam with bupivacaine prolongs the duration of analgesia when administered intrathecally but does not prevent hypotension. The objective of this study was to assess the effect of a combination
M Mohta et al.
Anaesthesia and intensive care, 37(4), 568-570 (2009-08-18)
This study was designed to determine the minimum effective dose (ED50) of mephentermine for prevention of post-spinal hypotension in women undergoing elective caesarean section. Dixon's up-down method of sequential allocation was used to determine the patient's dose of vasopressor drug.
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