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Merck
CN

M4302

Sigma-Aldrich

Anti-Matrix Metalloproteinase-1, C-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-MMP-1

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About This Item

MDL number:
MFCD01094314
UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

concentration

~1 mg/mL

technique(s)

western blot: 1:1,000 using a concentrated cell culture medium from a stimulated human cell line (M2928)

UniProt accession no.

P03956

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP1(4312)

Immunogen

synthetic peptide corresponding to C-terminal human matrix metalloproteinase-1 (interstitial collagenase).

Biochem/physiol Actions

By immunoblotting against the reduced protein, the antibody reacts with bands at 53 kDa and 51 kDa (the pro-form), as well as active forms. Also reacts with non-reduced MMP-1. Since the hemopexin domain is cleaved off to form the smallest active form of MMP-1, the antibody does not recognize the 21 kDa form of MMP-1.

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

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Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H319,H334

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
016K1342
025K1128
093K1232

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