M4545
L-Methionine γ-lyase from Pseudomonas putida
lyophilized powder, pkg of ≥1.0 units/vial
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About This Item
CAS Number:
EC Number:
255-916-5
UNSPSC Code:
12352204
MDL number:
form
lyophilized powder
packaging
pkg of ≥1.0 units/vial
storage temp.
−20°C
Other Notes
One unit will release 1.0 μmol of α-ketobutyrate from L-methionine per min at pH 8.0 at 37 °C.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
QC Methods
[Perspectives of developing enzyme-based antitumor drugs].
V S Pokrovskiĭ et al.
Voprosy onkologii, 57(2), 155-164 (2011-08-04)
Wei Fu et al.
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 28(4), 839-842 (2011-09-23)
Methionine-dependent increase in tumor cells is a specific metabolic defect. This metabolic defect is also a target for selective treatment of cancer. Studies found that the methionine gamma-lyase (methioninase, L-methionine gamma-lyase) can specificly split the methionine of extracellular and intracellular
Ashraf S A El-Sayed
Journal of microbiology (Seoul, Korea), 49(1), 130-140 (2011-03-04)
L-Methioninase was purified to electrophoretic homogeneity from cultures of Aspergillus flavipes using anion-exchange and gel filtration chromatography by 12.1 fold compared to the crude enzyme preparation. The purified enzyme had a molecular mass of 47 kDa under denaturing conditions and