M5064
Rp-2′-O-Monobutyryladenosine 3′,5′-cyclic monophosphorothioate
≥97% (HPLC), solid
Synonym(s):
Rp-2′-O-MB-cAMPS
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About This Item
assay
≥97% (HPLC)
form
solid
mol wt
apparent mol wt 437.3 Da
packaging
vial of 5 μmol (approx. 2 mg)
storage temp.
−20°C
SMILES string
CCCC(=O)O[C@@H]1[C@@H]2OP(O)(=S)OC[C@H]2O[C@H]1n3cnc4c(N)ncnc34
InChI
1S/C14H18N5O6PS/c1-2-3-8(20)24-11-10-7(4-22-26(21,27)25-10)23-14(11)19-6-18-9-12(15)16-5-17-13(9)19/h5-7,10-11,14H,2-4H2,1H3,(H,21,27)(H2,15,16,17)/t7-,10-,11-,14-,26?/m1/s1
InChI key
XSAXBAAZBXKFFH-IDYJAONBSA-N
Application
Eliminates first messenger-stimulated phosphorylation by cyclic AMP-dependent protein kinase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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U M Vischer et al.
Blood, 91(1), 118-127 (1998-02-07)
von Willebrand factor (vWF) is stored and released from endothelial secretory granules called Weibel-Palade (WP) bodies. Acute release can be induced by thrombin, histamine, and other mediators of thrombosis or inflammation. Their effect is thought to be mediated by an