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Merck
CN

M5427

Anti-Matrix Metalloproteinase-9 Hinge Region antibody produced in rabbit

~0.2 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-MMP-9

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About This Item

UNSPSC Code:
12352203
MDL number:
MFCD02570699

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

concentration

~0.2 mg/mL

technique(s)

immunoprecipitation (IP): suitable, indirect ELISA: 0.1-1.0 μg/mL, western blot: 0.5-2 μg/mL using PMA stimulated A431 cells

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... MMP9(4318)

Immunogen

synthetic peptide corresponding to the hinge region (surrounding amino acid 475) of human matrix metalloproteinase-9 (gelatinase-B).

Biochem/physiol Actions

By immunoblotting, the antibody reacts with a major band at 65 kDa and faint band at approx. 92 kDa in a PMA whole cell lysate.

Physical form

Solution in phosphate buffered saline containing 0.05% sodium azide.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H319,H334

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
087K1957
067K1293
076K1718
045K1410
120K1548

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Jamie Berger et al.
Neurological research, 29(6), 610-614 (2007-05-31)
High mortality incidence after serious systemic thermal injury is believed to be linked to significant increases in cerebral permeability, ultimately leading to irreversible blood-brain barrier (BBB) breakdown. The aim of this study was to investigate whether disruption of microvascular integrity
Manikantan S Kiran et al.
Vascular cell, 3(1), 6-6 (2011-02-26)
The mechanism of cell-cell contact dependent regulation of pericellular proteolysis in angiogenesis was examined by studying the expression of MMPs using isolated HUVECs in culture. Zymography, Immunoblot and RT-PCR analysis showed that the production and secretion of matrixmetalloproteinase-2 and matrixmetalloproteinase-9

Related Content

Data Sheet - M5427

Instructions

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