All Photos(1)

Key Documents

COO/COA

View All Documentation

M5808

Anti-Matrix Metalloproteinase-14, N-Terminal antibody produced in rabbit

Name: Anti-Matrix Metalloproteinase-14, N-Terminal antibody produced in rabbit
Brand: SIGMA

0.5 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-MMP-14

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

MDL number:

MFCD03097005

UNSPSC Code:

12352203

NACRES:

NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~65 kDa

species reactivity

human

concentration

0.5 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 using human cancer tissue
indirect ELISA: 1:1,000
western blot: 1:100-1:500 using A375 lysate

UniProt accession no.

P50281

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP14(4323)

General description

Matrix metalloproteinase-14 (MMP-14) is a collagenase localized to the cell membrane. The gene encoding it is present on human chromosome 14.

Immunogen

synthetic peptide corresponding to amino acids 185-299 in the N-terminal region of human matrix metalloproteinase-14 (membrane-type matrix metalloproteinase-1), conjugated to KLH.

Application

Anti-matrix metalloproteinase-14, N-terminal antibody produced in rabbit has been used for western blotting at a dilution of 1:100.

Biochem/physiol Actions

Matrix metalloproteinase-14 (MMP-14) aids in the migration of leukocytes and breaks down collagen. Migration of cells through the extracellular matrix is also mediated by it. MMP-14 has been shown to be associated with tuberculosis and glioma.

Physical form

Solution in phosphate buffered saline containing 0.09% (w/v) sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service