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Merck
CN

M6286

4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester

Synonym(s):

4-(4-Maleimidophenyl)butyric acid N-succinimidyl ester, 4-(4-Maleimidophenyl)butyric acid NHS ester, N-Succinimidyl 4-(4-maleimidophenyl)butyrate, SMPB

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About This Item

Empirical Formula (Hill Notation):
C18H16N2O6
CAS Number:
Molecular Weight:
356.33
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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reaction suitability

reagent type: cross-linking reagent

storage temp.

2-8°C

SMILES string

O=C(CCCc1ccc(cc1)N2C(=O)C=CC2=O)ON3C(=O)CCC3=O

InChI

1S/C18H16N2O6/c21-14-8-9-15(22)19(14)13-6-4-12(5-7-13)2-1-3-18(25)26-20-16(23)10-11-17(20)24/h4-9H,1-3,10-11H2

InChI key

PMJWDPGOWBRILU-UHFFFAOYSA-N

Application

Heterobifunctional cross-linking reagent.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

This item has


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Jay H Russell et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(38), 16405-16409 (2009-10-07)
Eukaryotes and bacteria regulate the activity of some proteins by localizing them to discrete subcellular structures, and eukaryotes localize some RNAs for the same purpose. To explore whether bacteria also spatially regulate RNAs, the localization of tmRNA was determined using
Yongbin Bang et al.
Biochemical and biophysical research communications, 530(3), 581-587 (2020-08-06)
Here, we report genetically encoded AviTag conjugating system for Channelrhodopsin-2(ChR2) in order to attach various nanostructures to the membrane protein in a cell type specific manner. First, AviTag peptide sequence is cloned to N-terminal site of ChR2 construct and expressed
A Cartaud et al.
The Journal of biological chemistry, 273(18), 11321-11326 (1998-06-06)
The accumulation of dystrophin and associated proteins at the postsynaptic membrane of the neuromuscular junction and their co-distribution with nicotinic acetylcholine receptor (AChR) clusters in vitro suggested a role for the dystrophin complex in synaptogenesis. Co-transfection experiments in which alpha-
P M Selzer et al.
Experimental parasitology, 87(3), 212-221 (1997-11-26)
The crystal structures of papain, cruzain, and human liver cathepsin B were used to build homology-based enzyme models of a cathepsin L-like cysteine protease (cpL) and a cathepsin B-like cysteine protease (cpB) from the protozoan parasite Leishmania major. Although structurally
M A Slinkin et al.
Nuclear medicine and biology, 20(4), 443-452 (1993-05-01)
F(ab')2 fragments of anti-carcinoembryonic antigen (CEA) monoclonal antibody (mAb) were modified with three chain-terminal polylysine-based chelating polymers so as to carry different electron charges. Immunoreactive conjugates labeled with 111In up to a specific radioactivity of 120-140 microCi/micrograms were injected into

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