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Merck
CN

M6302

Sigma-Aldrich

Anti-Matrix Metalloproteinase-2, N-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-MMP-2

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

concentration

~1 mg/mL

technique(s)

western blot: 1:1,000 using a concentrated cell culture medium from a stimulated human cell line (M 2928)

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... MMP2(4313)

Immunogen

synthetic peptide corresponding to the N-terminal end of human matrix metalloproteinase-2 (gelatinase-A)

Biochem/physiol Actions

By immunoblotting against the reduced protein, the antibody reacts with bands at 72 kDa and 68 kDa (the pro-form and active form). It does not react well with non-reduced MMP-2.

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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S Asha Nair et al.
Journal of cancer research and clinical oncology, 129(2), 123-131 (2003-04-02)
To study the role of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in cervical tumorigenesis, we analyzed 70 cervical tissue specimens that included 15 low-grade squamous intraepithelial lesions (SILs), 20 high-grade SILs, 25 squamous cell carcinomas (SCCs) and
Dmitri Gourevitch et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 226(2), 377-387 (2003-01-31)
The MRL mouse was proposed as a model of mammalian regeneration because it can close ear holes completely with the restoration of normal tissue. This regeneration process involves the formation of a blastema during healing, the re-appearance of cartilage and

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