Key Documents

View All Documentation

M6552

Monoclonal Anti-Matrix Metalloproteinase-3 antibody produced in mouse

Name: Monoclonal Anti-Matrix Metalloproteinase-3 antibody produced in mouse
Brand: SIGMA

clone SL-1 IIIC4, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-MMP-3

Select a Size

Change View

About This Item

UNSPSC Code:

12352203

MDL number:

MFCD01094317

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

SL-1 IIIC4, monoclonal

form

buffered aqueous solution

mol wt

antigen ~48 kDa (active form), antigen ~57 kDa (latent form)

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 using heat/pressure cooker pre-treatment, immunohistochemistry (frozen sections): 1:50-1:100, immunoprecipitation (IP): 10 using protein lysate (μL/mg), indirect immunofluorescence: 4-5 μg/mL, western blot: 1:200-1:400 using conditioned medium from PMA-treated HT-1080 cells or bladder, breast, or ovarian carcinoma

isotype

IgG1

UniProt accession no.

P08254

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... MMP3(4314)

Immunogen

APMA-activated human matrix metalloproteinase-3 (stromelysin-1).

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Physical form

Solution in 10 mM phosphate buffered saline and 0.2% bovine serum albumin, pH 7.4, containing 0.1% sodium azide.

Not finding the right product?

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.

Toru Ishibashi et al.

International immunopharmacology, 21(2), 468-473 (2014-06-15)

The aim of this study was to demonstrate the safety and efficacy of H2-saline infusion for treatment of rheumatoid arthritis (RA). We conducted a randomized, double-blind, placebo-controlled investigation of the infusion of 1 ppm H2-dissolved saline (H2-saline) in 24 RA

Identification and validation of genes involved in cervical tumourigenesis.

Thangarajan Rajkumar et al.

BMC cancer, 11, 80-80 (2011-02-23)

Cervical cancer is the most common cancer among Indian women. This cancer has well defined pre-cancerous stages and evolves over 10-15 years or more. This study was undertaken to identify differentially expressed genes between normal, dysplastic and invasive cervical cancer.

MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices.

W Brian Saunders et al.

Journal of cell science, 118(Pt 10), 2325-2340 (2005-05-05)

Previous work has shown that endothelial cell (EC)-derived matrix metalloproteinases (MMPs) regulate regression of capillary tubes in vitro in a plasmin- and MMP-1 dependent manner. Here we report that a number of serine proteases can activate MMP-1 and cause capillary

Trabecular cell expression of fibronectin and MMP-3 is modulated by aqueous humor growth factors.

Brenda J Tripathi et al.

Experimental eye research, 78(3), 653-660 (2004-04-27)

We investigated the mRNA and protein expression of fibronectin and stromelysin-1 (matrix metalloproteinase-3, MMP-3) by trabecular cells treated with growth factors present in primary and secondary aqueous humors. Serum-deprived trabecular cells were incubated for 48 hr or 7 days in

Effects of chronic sleep deprivation on the extracellular signal-regulated kinase pathway in the temporomandibular joint of rats.

Chuan Ma et al.

PloS one, 9(9), e107544-e107544 (2014-09-17)

To examine the possible involvement and regulatory mechanisms of extracellular signal-regulated kinase (ERK) pathway in the temporomandibular joint (TMJ) of rats subjected to chronic sleep deprivation (CSD). Rats were subjected to CSD using the modified multiple platform method (MMPM). The

View All Related Papers