M6567
Monoclonal Anti-MRP3 antibody produced in mouse
250 μg/mL, clone M3II-21, tissue culture supernatant
Synonym(s):
Anti-Multidrug Resistance Associated Protein 3
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Conjugate:
unconjugated
Clone:
M3II-21, monoclonal
Application:
ICC, IHC (f), WB
Citations:
1
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
tissue culture supernatant
antibody product type
primary antibodies
clone
M3II-21, monoclonal
mol wt
antigen 190-200 kDa
species reactivity
human
concentration
250 μg/mL
technique(s)
immunocytochemistry: 1:20-1:50 using acetone- or formaldehyde-fixed cytospin preparations, immunohistochemistry (frozen sections): 1:20 using acetone-fixed sections, western blot: 1:20-1:50
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ABCC3(8714)
General description
Multidrug Resistance-Associated Protein (MRP) is a seven member subfamily of ABC (ATP-binding cassette) transporters. MRP1, 2, and 3 have a similar structure with the ability to transport glutathione and glucuronate conjugates. MRP4 and MRP5 share more structure similarity with each other than with MRP1, 2, and 3. MRP4 and MRP5 also have the ability to transport cyclic nucleotides..The monoclonal anti-MRP3 recognizes human Multidrug Resistance-Associated Protein 3 (MRP3, 190-200 kDA)..
Immunogen
fusion protein of MRP3 (amino acids 830-949).
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
The antibody may be used in immunocytochemistry, immunoblotting, immunohistochemistry.
Biochem/physiol Actions
Reacts with an internal epitope of MRP3. Does not cross-react with the human MDR1, MRP1, MRP2, or MRP5 gene products.
Physical form
Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.
Preparation Note
Monoclonal Anti-Multidrug Resistance-Associated Protein 3 (MRP3), mouse isotype IgG1, derived using M3II-21 hybridoma produced by fusion SP2/O mouse myeloma cells and Balb/c mouse lymph nodes cells immunized with amino acids 830-949 of the human MRP3 bacterial fusion protein. The antibody is concentrated from culture supernatant of M3II-21 hybridoma cells grown in a bioreactor.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
Try our Product Selector Tool to narrow your options
Storage Class
10 - Combustible liquids
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Junro Kataoka et al.
Oncology reports, 35(5), 2576-2582 (2016-03-18)
Runt-related transcription factor 3 (RUNX3) is known to function as a tumor suppressor in gastric cancer and other types of cancers, including hepatocellular carcinoma (HCC). However, its role has not been fully elucidated. In the present study, we aimed to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M6567-1ML | 04061838079312 |