M6877
α-Methyl-DL-serine
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About This Item
Empirical Formula (Hill Notation):
C4H9NO3
CAS Number:
Molecular Weight:
119.12
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
226-565-5
MDL number:
InChI key
CDUUKBXTEOFITR-UHFFFAOYSA-N
InChI
1S/C4H9NO3/c1-4(5,2-6)3(7)8/h6H,2,5H2,1H3,(H,7,8)
SMILES string
CC(N)(CO)C(O)=O
assay
≥98% (TLC)
form
powder
color
white
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Biochem/physiol Actions
α-Methyl-DL-serine is an amino acid derivative.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Francisco Corzana et al.
Chemical communications (Cambridge, England), 47(18), 5319-5321 (2011-04-01)
A novel Tn antigen mimic, in which the natural underlying amino acid has been replaced by the non-natural α-methylserine analogue, is reported. This derivative exhibits a similar affinity for a natural lectin as for the natural Tn and retains the
Ewa Zabłotna et al.
Biochemical and biophysical research communications, 340(3), 823-828 (2005-12-29)
In many complexes formed by serine proteinases and their inhibitors, the hydroxyl group provided by water molecule or by the inhibitor Ser residue is located close to the inhibitor P1-P1' reactive site. In order to investigate the role of this
I S Mendelson
Journal of mental deficiency research, 26 (Pt 2), 107-110 (1982-06-01)
An inherited defect in the glycine cleavage enzyme results in the condition of neonatal glycine encephalopathy which has not responded to the current innovative methods of therapy. A re-examination of the enzyme structure and metabolic pathways, leads us to recommend
H Mickos et al.
Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 46(10), 989-993 (1992-10-01)
The three-dimensional structure of the RGD-adhesion sequence has been studied previously by means of linear and cyclic peptides. These peptides show widely differing affinities to integrins, ascribed to a strong dependence on steric factors in the receptor recognition. Insertion of
Yong-Chul Jeong et al.
Organic & biomolecular chemistry, 9(19), 6663-6669 (2011-08-17)
An efficient strategy for the control of the chemoselectivity in Dieckmann ring closures leading to tetramic acids derived from serine and α-methyl serine is reported, and this provides pathways to diversely substituted systems from a common starting material.
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