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Merck
CN

M7259

4-Methylumbelliferyl palmitate

Synonym(s):

Palmitic acid 4-methylumbelliferyl ester

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About This Item

Empirical Formula (Hill Notation):
C26H38O4
CAS Number:
Molecular Weight:
414.58
EC Number:
241-695-2
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4884046
MDL number:
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InChI

1S/C26H38O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(27)29-22-17-18-23-21(2)19-26(28)30-24(23)20-22/h17-20H,3-16H2,1-2H3

InChI key

QKQVFFACWLFRRX-UHFFFAOYSA-N

SMILES string

CCCCCCCCCCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

form

solid

mp

77 °C (lit.)

fluorescence

λex 360 nm; λem 449 nm in 0.1 M phosphate pH 8.0

storage temp.

−20°C

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Application

Fluorogenic substrate for acid lipase in human leukocytes.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Francis Aguisanda et al.
Orphanet journal of rare diseases, 12(1), 120-120 (2017-07-01)
Wolman disease (WD) is a rare lysosomal storage disorder that is caused by mutations in the LIPA gene encoding lysosomal acid lipase (LAL). Deficiency in LAL function causes accumulation of cholesteryl esters and triglycerides in lysosomes. Fatality usually occurs within
M W Baillargeon et al.
Lipids, 26(10), 831-836 (1991-10-01)
Lipases from Geotrichum candidum NRRL Y-553 are of interest because of their unique specificity for cis-9-unsaturated fatty acids relative to both stearic and palmitic acids. The lipases were partially purified by chromatography on Octyl Sepharose, AG MP-1 macroporous anion exchanger

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