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Merck
CN

M7574

Sigma-Aldrich

Mezlocillin sodium

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About This Item

Empirical Formula (Hill Notation):
C21H24N5NaO8S2
CAS Number:
42057-22-7
Molecular Weight:
561.56
EC Number:
255-640-5
UNSPSC Code:
51101500
NACRES:
NA.85

Key Documents

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description

Assay:per USP 838 μg/mg - 978μg/mg (calculated on anhydrous basis)

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

InChI

1S/C21H25N5O8S2.Na/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34;/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30);/t12-,13-,14+,17-;/m1./s1

InChI key

SGVORSZSYKDVFT-ZBJAFUORSA-N

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Biochem/physiol Actions

Mezlocillin is broad spectrum penicillin belonging to β-lactam class of antibiotics. It interferes with the synthesis of bacterial cell wall by binding to penicillin-binding proteins (PBPs).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
112M4032V
14121103
088M4864V

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Dilip Nathwani et al.
Drugs, 45(6), 866-894 (1993-06-01)
The penicillins are a large group of bicyclic ring compounds which contain a 4-membered beta-lactam ring (penams) fused to a 5-membered thiazolidine ring. Benzylpenicillin (penicillin G) was the first natural penicillin with potent activity against all Gram-positive pathogens, Gram-negative cocci
Review of the pharmacokinetics of mezlocillin.
T Bergan
The Journal of antimicrobial chemotherapy, 11 Suppl C, 1-16 (1983-05-01)

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