M7699
Mafenide Acetate
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About This Item
Empirical Formula (Hill Notation):
C9H14N2O4S
CAS Number:
Molecular Weight:
246.28
UNSPSC Code:
51101500
InChI key
UILOTUUZKGTYFQ-UHFFFAOYSA-N
InChI
1S/C7H10N2O2S.C2H4O2/c8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4)
form
powder
color
white
solubility
DMSO: soluble 1 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
enzyme | inhibits
storage temp.
−20°C
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Biochem/physiol Actions
Mafenide is a bacteriostatic antibiotic with a broad activity against Gram positive, Gram negative bacteria and Clostridia. Mafenide acetate penetrates eschar and prevents heavy colonization in burn wounds.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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María Teresa Rosanova et al.
Archivos argentinos de pediatria, 110(4), 298-303 (2012-08-04)
Topical agents are widely used in the care of burn patients; however the efficacy to prevent local infections and/or sepsis has not been clearly established in studies with a high level of evidence. This systematic review was conducted to assess
H Maghsoudi et al.
Annals of burns and fire disasters, 24(3), 132-137 (2012-03-08)
Histological and clinical studies of wound healing were performed in comparable cases of fresh partial-thickness burns treated with honey dressing or mafenide acetate in two groups of 50 randomly allocated patients. Of the patients with honey-treated wounds, 84% showed satisfactory
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