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Merck
CN

M7750

Mercury Orange

powder

Synonym(s):

1-(4-Chloromercuriophenylazo)-2-naphthol

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About This Item

Empirical Formula (Hill Notation):
C16H11ClHgN2O
CAS Number:
Molecular Weight:
483.31
UNSPSC Code:
12171500
PubChem Substance ID:
EC Number:
221-358-6
MDL number:
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form

powder

color

dark red

SMILES string

Oc1ccc2ccccc2c1\N=N\c3ccc([Hg]Cl)cc3

InChI

1S/C16H11N2O.ClH.Hg/c19-15-11-10-12-6-4-5-9-14(12)16(15)18-17-13-7-2-1-3-8-13;;/h2-11,19H;1H;/q;;+1/p-1/b18-17+;;

InChI key

CDEIGFNQWMSEKG-QIKYXUGXSA-M

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

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Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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A Coates et al.
Melanoma research, 5(2), 107-111 (1995-04-01)
Because the resistance of melanoma to cytotoxic therapy may be due to high intracellular glutathione (GSH), we wished to monitor GSH in melanoma cells during treatment. This required an assay suitable for very small samples. So we chose analytical flow
P Chieco et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 31(7), 975-976 (1983-07-01)
We performed glutathione (GSH) staining at a low temperature to prevent GSH release from the section and, hence, improve morphology. Fresh frozen sections of liver, lung, kidney, heart, and stomach were incubated for GSH activity in an ice bath (2-5
David W Hedley et al.
International journal of radiation oncology, biology, physics, 61(1), 137-144 (2005-01-05)
The non-protein sulfydryls (NPSH) glutathione and cysteine are able to effect chemical repair of radiation-induced DNA damage, particularly under hypoxic conditions, and are implicated in radioresistance. The levels of NPSH in the nucleus are predicted to be more important than
M J Beck et al.
Toxicological sciences : an official journal of the Society of Toxicology, 62(1), 92-102 (2001-06-16)
Glutathione (GSH), cysteine, and other low-molecular-weight thiols (LMWT) play a vital role in the detoxication of xenobiotics and endogenous chemicals. Differential alterations of LMWT status in various cell types of the developing embryo may underlie cell-specific sensitivity or resistance to
A Larrauri et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 35(2), 271-274 (1987-02-01)
Thiol groups of glutathione react with the organomercurial azo dye mercury orange at a faster rate than with -SH groups of proteins. This property makes possible visualization of glutathione in cells without appreciable interference from other -SH groups. To render

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