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Merck
CN

M7920

Minoxidil Sulfate

K+ channel opener, powder

Synonym(s):

U-58838

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About This Item

Empirical Formula (Hill Notation):
C9H15N5O4S
CAS Number:
Molecular Weight:
289.31
UNSPSC Code:
12352107
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
powder
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Product Name

Minoxidil Sulfate,

form

powder

Quality Segment

originator

Johnson & Johnson

storage temp.

−20°C

SMILES string

Nc1cc(nc(N)[n+]1OS([O-])(=O)=O)N2CCCCC2

InChI

1S/C9H15N5O4S/c10-7-6-8(13-4-2-1-3-5-13)12-9(11)14(7)18-19(15,16)17/h6H,1-5H2,(H4,10,11,12,15,16,17)

InChI key

OEOLOEUAGSPDLT-UHFFFAOYSA-N

Application

Minoxidil sulfate (MXS) has been used as a drug agent to study its effects on alopecia in corticotropin-releasing factor over-expressing (CRF-OE) mice. It has also been used as a positive control in an assay for the culturing of rat vibrissa follicles.

Biochem/physiol Actions

Minoxidil sulfate (MXS) is an endogenous derivative of minoxidil. It possesses greater aqueous solubility and is a potent vasodilator. MXS has the potential to treat androgenic alopecia or male baldness.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Active metabolite of minoxidil.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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