M8009
Tyr-[Trp2]-Melanocyte Stimulating Hormone Release Inhibiting Factor trifluoroacetate salt
≥97% (HPLC)
Synonym(s):
[Tyr0, Trp2]-MIF-I, Tyr-W-MIF-I
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C27H32N6O5
CAS Number:
Molecular Weight:
520.58
UNSPSC Code:
12352200
assay
≥97% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
Mixed agonist/antagonist at opiate receptors
Other Notes
Originally isolated from human frontal cortex and from bovine hypothalamus
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
K A Gergen et al.
Peptides, 15(8), 1505-1511 (1994-01-01)
Tyr-W-MIF-1 is a tetrapeptide recently isolated from brain that has opiate modulating activity. In this study, we used immunocytochemical (ICC) detection of FOS proto-oncogene protein to map brain areas activated by an ICV injection of Tyr-W-MIF-1 (200 micrograms). The analgesic
J E Zadina et al.
Neuroscience letters, 155(2), 220-222 (1993-06-11)
A peptide recently isolated from human and bovine brain, Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2), was tested for its effects on nociception in the tail-flick test after intracerebroventricular injection in the rat. Tail-flick latencies were significantly increased with a rapid onset and remained significantly
W A Banks et al.
Journal of neuroscience research, 35(6), 690-695 (1993-08-15)
Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2). Despite similarities in structure, Tyr-MIF-1 and MIF-1 can act differently in behavioral, blood-brain barrier (BBB) transport, and receptor binding systems.
J Erchegyi et al.
Peptide research, 6(1), 31-38 (1993-01-01)
Analogs of the naturally occurring peptides Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and Tyr-W-MIF-1 (Tyr-Pro-Trp-GLy-NH2) were synthesized and investigated for their opiate agonist as well as antagonist activity in the guinea pig ileum assay. [Tyr5]-Tyr-MIF-1 and the endogenous Tyr-W-MIF-1 were the most potent opiate
J E Zadina et al.
Nature, 386(6624), 499-502 (1997-04-03)
Peptides have been identified in mammalian brain that are considered to be endogenous agonists for the delta (enkephalins) and kappa (dynorphins) opiate receptors, but none has been found to have any preference for the mu receptor. Because morphine and other
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service