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Merck
CN

M8283

Supelco

Mesterolone

1.0 mg/mL in 1,2-dimethoxyethane

Synonym(s):

1α-Methylandrostan-17β-ol-3-one

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About This Item

Empirical Formula (Hill Notation):
C20H32O2
CAS Number:
Molecular Weight:
304.47
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
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form

liquid

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

1.0 mg/mL in 1,2-dimethoxyethane

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

single component solution

storage temp.

2-8°C

SMILES string

[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)[C@@H](C)CC(=O)C2

InChI

1S/C20H32O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h12-13,15-18,22H,4-11H2,1-3H3/t12-,13-,15-,16-,17-,18-,19-,20-/m0/s1

InChI key

UXYRZJKIQKRJCF-TZPFWLJSSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

26.6 °F

Flash Point(C)

-3 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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Karina Fontana et al.
Histology and histopathology, 23(11), 1367-1377 (2008-09-12)
The growing and indiscriminate use of high doses of anabolic androgenic steroid (AAS) among youth and athletes has raised serious concerns about its hepatotoxic effects. Herein, the influence of AAS in the nuclear phenotype of hepatocytes was investigated in sedentary
J Lim et al.
Molecular endocrinology (Baltimore, Md.), 14(8), 1187-1197 (2000-08-10)
The androgen receptor (AR) is a ligand-dependent X-linked nuclear transcription factor regulating male sexual development and spermatogenesis. The receptor is activated when androgen binds to the C-terminal ligand-binding domain (LBD), triggering a cascade of molecular events, including interactions between the
Karina Fontana et al.
Histology and histopathology, 27(11), 1449-1458 (2012-09-29)
Anabolic-androgenic steroids (AAS) and exercise share comparable effects on myogenic differentiation, force development, fiber growth and skeletal muscle plasticity. The participation of nitric oxide synthase (NOS) on these effects was only demonstrated in response to exercise. Using immunohistochemistry and western
Short-term treatment in sexual dysfunction: a review.
A J Cooper
Comprehensive psychiatry, 22(2), 206-217 (1981-03-01)
T M Itil
Progress in neurobiology, 20(3-4), 185-249 (1983-01-01)
Antidepressant properties of six compounds were predicted based on their computer-analyzed human electroencephalographical (CEEG) profiles. The clinical investigations with mianserin (GB-94) confirmed the CEEG prediction. This compound has now been marketed as the first antidepressant of which the clinical effects

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