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Merck
CN

M8648

Anti-Myoglobin antibody produced in rabbit

whole antiserum

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About This Item

UNSPSC Code:
12352203
MDL number:
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biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... MB(4151)

Immunogen

human myoglobin from skeletal muscle.

Application

Anti-Myoglobin antibody produced in rabbit is suitable for immunoblotting at a dilution of 1:500 -1:1000.

Biochem/physiol Actions

Myoglobin is an oxygen binding, cytoplasmic hemoprotein expressed in cardiomyocytes and skeletal muscle fibers. Myoglobin has high affinity for oxygen and is an ideal candidate for short term storage and delivery of oxygen in hypoxic conditions.

Preparation Note

Dilute with buffer: 0.05 M borate, pH 7.8, 5% normal rabbit serum and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Akiko Matsubara et al.
Journal of applied toxicology : JAT, 39(6), 919-930 (2019-02-16)
Glutathione (GSH) is one of the most extensively studied tripeptides. The roles for GSH in redox signaling, detoxification of xenobiotics and antioxidant defense have been investigated. A drug-induced rhabdomyolysis mouse model was recently established in L-buthionine-(S,R)-sulfoximine (BSO; a GSH synthesis
Akiko Matsubara et al.
Journal of applied toxicology : JAT, 39(6), 919-930 (2019-02-16)
Glutathione (GSH) is one of the most extensively studied tripeptides. The roles for GSH in redox signaling, detoxification of xenobiotics and antioxidant defense have been investigated. A drug-induced rhabdomyolysis mouse model was recently established in L-buthionine-(S,R)-sulfoximine (BSO; a GSH synthesis
Lisa Staunton et al.
Molecular bioSystems, 7(8), 2480-2489 (2011-06-02)
Myotonia is a symptom of various genetic and acquired skeletal muscular disorders and is characterized by hyperexcitability of the sarcolemma. Here, we have performed a comparative proteomic study of the genetic mouse models ADR, MTO and MTO*5J of human congenital
Katja Anttila et al.
The Journal of experimental biology, 216(Pt 7), 1183-1190 (2013-03-15)
In fishes, performance failure at high temperature is thought to be due to a limitation on oxygen delivery (the theory of oxygen and capacity limited thermal tolerance, OCLTT), which suggests that thermal tolerance and hypoxia tolerance might be functionally associated.
D K McMahon et al.
The American journal of physiology, 266(6 Pt 1), C1795-C1802 (1994-06-01)
We examined the myofibril biochemical, structural, and biophysical properties of C2C12, a mouse skeletal muscle cell line (American Type Culture Collection), to assess whether force development and the sensitivity of the myofilaments to calcium could be measured in C2C12 myotubes

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