M8655
Mast cell degranulating peptide HR1
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C71H133N19O15
CAS Number:
Molecular Weight:
1492.93
MDL number:
UNSPSC Code:
12352200
Assay
≥97% (HPLC)
composition
Peptide content, ~70%
storage temp.
−20°C
SMILES string
CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O
Amino Acid Sequence
Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Val-Lys-Lys-Val-Leu-NH2
Biochem/physiol Actions
Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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M U Tuĭchibaev et al.
Biokhimiia (Moscow, Russia), 53(2), 219-226 (1988-02-01)
Three 14-member linear peptides (HR-1, HR-2 and HR-3) capable of degranulating mast cells and thus initiating histamine release were isolated from the venom of the giant hornet Vespa orientalis, using reverse phase high performance liquid chromatography. The complete amino acid
Low molecular weight peptides from the venom of the giant hornet Vespa orientalis. Structure and function.
Tuichibaev, M.U.
Biochemica, 53, 219-219 (1988)
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