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Merck
CN

M8655

Mast cell degranulating peptide HR1

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C71H133N19O15
CAS Number:
Molecular Weight:
1492.93
UNSPSC Code:
12352200
MDL number:
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assay

≥97% (HPLC)

composition

Peptide content, ~70%

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

Biochem/physiol Actions

Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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M U Tuĭchibaev et al.
Biokhimiia (Moscow, Russia), 53(2), 219-226 (1988-02-01)
Three 14-member linear peptides (HR-1, HR-2 and HR-3) capable of degranulating mast cells and thus initiating histamine release were isolated from the venom of the giant hornet Vespa orientalis, using reverse phase high performance liquid chromatography. The complete amino acid
Low molecular weight peptides from the venom of the giant hornet Vespa orientalis. Structure and function.
Tuichibaev, M.U.
Biochemica, 53, 219-219 (1988)

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