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Merck
CN

M8779

4-Maleimidobutyric acid

≥98% (titration)

Synonym(s):

γ-Maleimidobutyric acid, 4-Maleimidobutanoic acid, N-(3-Carboxypropyl)maleimide, N-Maleoyl-4-aminobutyric acid, N-Maleoyl-GABA

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About This Item

Empirical Formula (Hill Notation):
C8H9NO4
CAS Number:
Molecular Weight:
183.16
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
1455876
MDL number:
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assay

≥98% (titration)

form

powder

color

beige

storage temp.

2-8°C

SMILES string

OC(=O)CCCN1C(=O)C=CC1=O

InChI

1S/C8H9NO4/c10-6-3-4-7(11)9(6)5-1-2-8(12)13/h3-4H,1-2,5H2,(H,12,13)

InChI key

NCPQROHLJFARLL-UHFFFAOYSA-N

Application

Modification reagent for thiol groups in proteins


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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D H Rich et al.
Journal of medicinal chemistry, 18(10), 1004-1010 (1975-10-01)
A method for the preparation of N-maleoylamino acids and esters is reported. These compounds were shown to inhibit both the oxytocin-induced smooth muscle contraction in the isolated rat uterus and the vasopressin-induced water loss from the isolated toad bladder. The