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Merck
CN

M8877

α-Methyl-DL-m-tyrosine

Synonym(s):

α-MMT, DL-2-Methyl-3-(3-hydroxyphenyl)alanine, AMMT

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About This Item

Empirical Formula (Hill Notation):
C10H13NO3
CAS Number:
Molecular Weight:
195.22
UNSPSC Code:
12352200
MDL number:
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SMILES string

CC(N)(Cc1cccc(O)c1)C(O)=O

storage temp.

−20°C

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R Boldry et al.
Pharmacology, biochemistry, and behavior, 24(2), 223-228 (1986-02-01)
We have previously synthesized a chemical analog of dopamine (DA) in which the amine group has been replaced by a permanently charged dimethylsulfonium group. In the present study, we have determined whether this compound can exert DA agonist activity in
J Bernabe et al.
Cellular and molecular neurobiology, 16(6), 617-624 (1996-12-01)
1. The present study aimed to develop a pharmacological model of catecholamine (CA) depletion in the hypothalamus during the period of its morphofunctional development, i.e. in fetal and neonatal rats of both sexes. 2. In the first series of experiments
S M Plosker et al.
The Journal of clinical endocrinology and metabolism, 73(3), 549-554 (1991-09-01)
The physiological role of catecholamines, particularly dopamine and norepinephrine, in the regulation of gonadotropin secretion in humans is unclear. We administered the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine (AMPT, 500 mg at 800 and 1000 h) to five women in the early
L Carlsson
Acta physiologica Scandinavica. Supplementum, 559, 1-85 (1987-01-01)
The present study was performed in order to examine some of the characteristics of the local impulse-independent release of noradrenaline (NA) seen in acute myocardial ischemia. Experiments were carried out mainly in isolated perfused rat hearts submitted to either global
L N Maslova et al.
Ontogenez, 15(3), 327-331 (1984-05-01)
The effects of daily intraperitoneal (150 mg/kg of body weight) injections of alpha-methyl-dl-tyrosine (MT), an inhibitor of tyrosine hydroxylase, on the 2nd to 4th, 5th to 7th or 10th to 12th days of life on the pituitary-adrenal function and brain

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