M9399
U-69593
Synonym(s):
(+)-(5α,7α,8β)-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]-benzeneacetamide, U69593
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About This Item
Empirical Formula (Hill Notation):
C22H32N2O2
CAS Number:
Molecular Weight:
356.50
UNSPSC Code:
41116107
MDL number:
InChI key
PGZRDDYTKFZSFR-ONTIZHBOSA-N
InChI
1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1
SMILES string
CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N3CCCC3)C(=O)Cc4ccccc4
storage temp.
2-8°C
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Biochem/physiol Actions
A kappa agonist
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M G Gillan et al.
British journal of pharmacology, 77(3), 461-469 (1982-11-01)
1 In homogenates of rat brain, the binding characteristics of tritiated opiates and opioid peptides were examined and the relative capacities of mu-, delta- and kappa-binding sites of the opiate receptor determined by saturation analysis.2 In competition experiments, binding of
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