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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
dermatological diseases
shipped in
wet ice
storage temp.
2-8°C
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General description
Hydroxyproline (4-hydroxyproline) is a non-proteinogenic amino acid formed by the post-translational hydroxylation of proline. Hydroxyproline is a major component of collagen, where it serves to stabilize the helical structure. Because hydroxyproline is largely restricted to collagen, the measurement of hydroxylproline levels can be used as an indicator of collagen content. Conditions that increase collagen turnover can elevate serum and urine hydroxyproline levels. Urine and serum hydroxyproline levels can be used as a marker for bone resorption.
Application
Hydroxyproline Assay Kit has been used to determine the concentration of hydroxyproline and collagen.
Suitable for hydroxyproline detection in cell and tissue culture supernatants, urine, plasma, serum, and other biological samples.
Biochem/physiol Actions
In the Hydroxyproline Assay Kit, hydroxyproline concentration is determined by the reaction of oxidized hydroxyproline with 4-(Dimethylamino)benzaldehyde (DMAB), which results in a colorimetric (560 nm) product, proportional to the hydroxyproline present.
signalword
Danger
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Ox. Liq. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 3
target_organs
Central nervous system, Thyroid
supp_hazards
Storage Class
5.1B - Oxidizing hazardous materials
flash_point_f
64.4 °F
flash_point_c
18 °C
Regulatory Information
危险化学品
易制爆化学品
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Instructions
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAK008-1KT | 04061835546930 |
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