MAK065
Lactate Assay Kit II
sufficient for 100 colorimetric tests
Synonym(s):
Lactic Acid Assay Kit
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 colorimetric tests
application(s)
cosmetics
food and beverages
detection method
colorimetric
relevant disease(s)
endocrinological disorders, diabetes; cancer
storage temp.
−20°C
General description
L(+)-Lactate is a metabolic compound formed in animals by the action of the enzyme Lactate Dehydrogenase. Lactate is produced in proliferating cells and during anaerobic conditions such as exercise. Abnormally high concentrations of lactate have been related to pathological conditions such as cancer, diabetes, and lactate acidosis. L(+)-Lactate is the major stereoisomer of lactate formed in human intermediary metabolism and is present in blood at levels of around 1-2 mmol/L. This kit provides a convenient means for detecting L(+)-Lactate in biological samples.
Application
Lactate Assay Kit II has been used to measure the levels of lactate in samples.
Suitable for detecting L(+)-Lactate in culture medium, fermentation medium, blood and cells.
Biochem/physiol Actions
Lactate concentration is determined by an enzyme assay, which results in a colorimetric (450 nm) product, proportional t the lactate present. There is no need of pretreatment or purification of samples. Typical sensitivities of detection are between 0.02-10 mM of lactate.
signalword
Danger
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
hcodes
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
Regulatory Information
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Articles
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
Yan Jouroukhin et al.
Translational psychiatry, 8(1), 76-76 (2018-04-13)
Our knowledge of how genetic risk variants contribute to psychiatric disease is mainly limited to neurons. However, the mechanisms whereby the same genetic risk factors could affect the physiology of glial cells remain poorly understood. We studied the role of
Metabolic engineering of Methanosarcina acetivorans for lactate production from methane
McAnulty M J, et al.
Biotechnology and Bioengineering, 114(4), 852-861 (2017)
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders.
Jouroukhin Y, et al.
Translational Psychiatry, 8(1), 76-76 (2018)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAK065-1KT | 04061834065074 |